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Additionally, BMP-7 downregulated miR-21 and upregulated Smad7 at both the transcript and protein levels [77]

2 Mitochondrial dysfunctions in kidney diseases 2.1 Mitochondrial homeostasis imbalance Mitochondrial quality control (MQC) is an elaborate mechanism to maintain homeostasis, ensuring the enough numbers of functional mitochondria (Pickles et al., 2018

Although further clinical research is needed to determine optimal timing, integrating this temporal dimension represents a promising frontier for personalized exercise prescriptions aimed at maximizing redox homeostasis