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Furthermore, the ability of decanoic acid to reduce mTOR activity within astrocytes serves as an added benefit ( While modulating lipid metabolism has shown promise in some individuals with MCD and epilepsy, altering lipid metabolism in certain focal epilepsies may not allow for efficient utilization of brain lipids and may lead to increased neuronal excitability ( PIK3C2B - which encodes for the class II phosphatidylinositol 3-kinase PI3K-C2-beta, a ubiquitously expressed PI3K protein ( PIK3C2B missense loss-of-function mutations, affecting either the catalytic or the lipid-binding domains of the lipid kinase

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The absorbance was read at 340 nm using a blank solution excluding the protein and activity was determined using molar extinction coefficient of NADP(H) as 6.22 10 3 Lmol 1 cm