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Peer review Peer review information Nature Communications thanks Jing Yang, Vinayak Khodade and the other anonymous reviewer(s) for their contribution to the peer review of this work

Vitamins C and E are known for their antioxidant properties, which help combat oxidative stress (Myhrstad and Wolk, 2023)

edodes showed the highest DPPH inhibition and TPC

Nobiletin , a flavone found in citrus peels, exerted anti-inflammatory effects in TNBS-induced colitis through the downregulation of iNOS and COX-2 expression, restoring barrier function through the inhibition of the Akt-NF-B-MLCK pathway [111]