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Lin Xu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Y., Ko, J

Qualitative screening tests for G6PD deficiency include: Fluorescence spot Dye decolourisation Analytical variables affecting G6PD tests: Reticulocytes have higher concentrations of G6PD, so tests performed after a recent haemolytic episode may produce false negatives Anaemia and leukocytosis also interfere with screening tests Recent red cell transfusion A positive screening test should be followed by a quantitative assay Women suspected of having G6PD deficiency should be tested by quantitative assay as the screening tests may produce false negatives

NBDHEX simultaneously activates JNK and TRAF2, interfering with the effect of GST via two different pathways, leading to cell-cycle arrest and cell death

Additionally, overcoming key obstacles such as the BBB and drug efflux is crucial for improving drug delivery and minimizing tumor recurrence