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10.1021/jf8009238

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Targeted antioxidants such as mitochondria-targeted coenzyme Q10 (MitoQ) have been evaluated in clinical studies for HF with preserved ejection fraction, confirming their safety and potential efficacy in improving myocardial energy reserves, which accumulate within the organelle to neutralize reactive species at their source (ClinicalTrials.gov ID [NCT03960073])

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