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IGF-1 activates the mTOR signaling pathway that drives muscle protein synthesis, supports connective tissue repair, and promotes satellite cell activation for muscle regeneration

Tachyphylaxis to flushing typically occurs within a few days

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(Growth Hormone and IGF Research, 2003) documented that peptide therapy targeting the somatotropic axis in subjects with growth hormone deficiency produced measurable fat reduction, lean muscle preservation, and improvements in bone mineral parameters

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