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During the follow-up period, rebleeding occurred in 10 (23.8%) and 21 (41.2%) GVO and GVO+BB patients, respectively, and 39 patients died [23 (54.8%) in the GVO group and 16 (31.4%) in the GVO+BB group]

Clinical Potential This review has introduced a few of the many disorders afflicting peripheral tissues or the CNS in which inflammation is implicated, but that is enough to recognize the therapeutic potential of influencing the kynurenine pathway by pharmacological interference

ESM 1 (download DOCX (DOCX 159 KB) ESM 2 (download DOCX (DOCX 269 KB) Rights and permissions Springer Nature or its licensor (e.g

Circulatory system Heart injury (e.g., caused by myocardial infarction, I/R, or anthracycline-based chemotherapy) is associated with an increased ferroptotic response with reduced GPX4 and increased iron accumulation