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1:1000), anti-ferroportin 1 (Fpn1

3.2.2 TGF--induced mitochondrial ROS production Mitochondria are the primary intracellular source of ROS, and TGF-1 markedly enhances their production across multiple cell types, contributing to apoptosis, senescence, epithelialmesenchymal transition (EMT), and fibrotic gene expression associated with myofibroblast differentiation [58]

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It has also been observed that after induction by the glucocorticosteroiddexamethasone, which has strong anti-inflammatory, antiallergic, and immunosuppressive effects and is used in dermatology for conditions, such as psoriasis and allergic skin diseases, the expression of CYP1A, CYP2B, CYP2E, and CYP3A is increased at the mRNA level [140, 144]

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