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There was no difference in the rate of major malformations between women exposed to PPIs and the control group, corresponding to a Relative Risk (RR)=1.04, [95% Confidence Interval (CI) 0.25-4.21]

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However, if monoamine oxidase (MAO) inhibitors are present, the duration may increase to one hour

Apoptosis Apoptosis is the most common noninflammatory form of programmed cell death [182, 255]

GCK also exerts joint protection by inhibiting the proliferation, migration and secretion of synovial cells (129), whose molecular mechanism is to inhibit the secretion of TNF- in AIA-FLS rats, down-regulate the expression of tumor necrosis factor receptor type 2 (TNFR2), and inhibit TNF--mediated proliferation, migration and secretion of AIA -FLS