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Though subsequent events after protein binding were cause for controversy initially (detailed in the section on ferroptosis), progress in resolving this issue was made when it was shown that an oxidant stress was not observed during metabolism of APAP [23, 24] but only after the drug metabolism phase was completed, and that the oxidant stress was located within mitochondria [25, 26]

A diferencia de otros compuestos, su estabilidad molecular le permite mantener su integridad en entornos gstricos y sistmicos, lo que lo convierte en un sujeto de estudio ideal para la investigacin de la regeneracin endgena