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Feng L, Li B, Cai M, Zhang Z, Zhao Y, Yong SS, Tian Z

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Therefore, important blood components, including plasma proteins, clotting factors, and platelets, are returned to the individual being treated

ROS generated during metabolic reprogramming (e.g., enhanced glycolysis, mitochondrial dysfunction) can amplify inflammatory signals, while inflammation further exacerbates metabolic dysregulationforming a vicious cycle of metabolic abnormalitiesinflammationimmune dysregulation (111)