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3) substitution of a non- -amino acid (e.g., -amino acid or ?-amino acid) at the N-terminal

The complex, multi-factorial pathogenesis of SAH, with intertwined pathways, strongly suggests that single-agent therapies may be insufficient to achieve sustained clinical benefit [14,31]

doi: 10.1016/S1470-2045(21)00630-6 330 PostowMACallahanMKBarkerCAYamadaYYuanJKitanoSet al

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In a study, it was reported that oral administration of 1.5 g MSM to rats for 90 days did not cause any side effects and mortality [47]