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The absence of FDA approval means no verified manufacturing standards, dosing protocols, or safety benchmarks exist for human use

Moreover, elevated serum arginase 1 (ARG1) levels are frequently observed in the serum of cancer patients, and are positively correlated with a poor prognosis [273]

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Most ALPS patients are affected by heterozygous germline mutations in the Fas cell surface death receptor gene ( FAS ) via autosomal dominant inheritance (Jackson et al., 2010)

Dosage may vary depending on factors such as age, weight, and overall health status