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Gastroenterology 158 , 18511864

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Finally, epigenetic regulatory networks are incompletely characterized: while individual ubiquitinases, miRNAs, or demethylases are implicated, the integrated epigenetic landscape governing ferroptosis in I/R AKI (e.g., crosstalk between ubiquitination and miRNA-mediated silencing, or epigenetic memory of ferroptosis susceptibility) remains unclear

In contrast, in a hypertensive nephropathy model, USP25 inhibited the TGF- signaling pathway by suppressing the ubiquitination process of Smad4, delaying renal fibrosis and protecting renal function[106]

These include peptides, SARMs, nootropics, post-cycle therapy compounds, and other research chemicals