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Lundin K, Bentzen JG, Bozdag G, et al

These serious side effects can occur with tirzepatide

Ferric iron (Fe 3+ ) is stored within ferritin in the cytoplasm, whereas Fe 2+ for ferroptosis induction is either imported via CD44 from the extracellular compartment [22] or provided via lysosomal ferritin degradation and subsequent reduction [23]

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The brain, despite representing only about 2% of body weight, consumes approximately 20% of the body's oxygen, generating substantial oxidative stress as a byproduct of its high metabolic activity