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doi:10.1155/2012/736837 Kumar P, Liu C, Suliburk J, Hsu JW, Muthupillai R, Jahoor F, Minard CG, Taffet GE, Sekhar RV

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Another study exhibited that acanthopanax senticosus polysaccharides, an important active component of Acanthopanax, reprogrammed ecological dysregulation triggered by arthritis progression and enhanced -glutamylcysteine synthetase expression, thus suppressing the nucleation of ASC to effectively block NLRP3 inflammasome activation and attenuate inflammatory arthritis (86)