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ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance

Compared to healthy controls, those with NAFLD who were not obese had statically elevated levels of glutamate, isoleucine and valine, while those with NAFLD who were obese had significantly elevated levels of glutamate, all BCAA, and significantly lower levels of glycine and serine

This suggests that NCOA4 in AD may be translocated to the cytoplasm, where it could induce the degradation of ferritin and increase sensitivity to ferroptosis [41]

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Results Animals and food intake At the start of the study, mean body weight of the animals was 243 g