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Future Prospects of GPX4 Research: Translational Potential of GPX4 in Clinical Therapy GPX4 holds significant therapeutic potential in oncology, particularly through its role in inducing ferroptosis in neoplastic cells that are resistant to traditional treatments

The N-hydroxy aryl amine N-glucuronide conjugate is thought to be excreted from the liver and to build up in the bladder lumen

These findings collectively underscore the multifaceted role of IGF1R in both metabolic regulation and EMT, suggesting that IGF1R may similarly influence EMT in the context of kidney stone formation

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