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Mobile phase B was 90% acetonitrile with 10 mM ammonium acetate, 0.1% ammonium hydroxide and 0.1% medronic acid

Additionally, MitoVitE treatment resulted downregulation of the Toll-like receptor (TLR) signaling cascade and the suppression of various key components for NFB downstream signalling, namely IBKB (inhibitor of nuclear factor kappa B kinase subunit beta), NFB1, MyD88 (myeloid differentiation primary response gene 88), and TRAF6 (TNF receptor-associated factor 6) (Minter et al., 2020)

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Patients were started on fondaparinux sodium injection 0.1 mg/kg once daily with doses rounded to the nearest prefilled syringe (2.5 mg, 5 mg, or 7.5 mg) for patients weighing over 20 kg