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miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer

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In the early stage of the disease, mitophagy mostly acts as an adaptive compensatory mechanism to play a protective role, while with the progression of the disease to the late stage, the regulatory mechanism of mitophagy is disrupted, often showing a state of excessive activation, thereby aggravating tissue damage

In addition to the root system, scRNA-seq has also been applied to study other important maize tissues, including female inflorescences (Xu et al., 2021), mesophyll (Tao et al., 2022), and shoot apices (Ma et al., 2025), further expanding our understanding of maize multi-tissue developmental processes and functional differentiation