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Once opened, it is typically used within a 28-day period

Tew et al., 2020

Atorvastatin appears to be the statin most commonly associated with a cholestatic pattern of liver injury

doi: 10.3389/fnagi.2016.00256

Signs Your Pet May Be Struggling with Toxic Overload While these can indicate many health conditions, the following symptoms warrant a veterinary assessment: Loss of appetite lasting more than 24 hours Persistent vomiting or diarrhoea Difficulty urinating or changes in urination frequency or colour Yellowing of the eyes or gums (jaundice - a sign of liver stress) Unexplained lethargy or significant behavioural changes Excessive drooling or difficulty swallowing Seizures or neurological signs Chronic skin issues, itching, or recurring ear infections A Word on Safe Detoxing: What to Avoid What works for humans can be dangerous - or even fatal - for pets