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Further exploration and clinical validation are necessary to fully understand these interactions and to integrate dietary strategies into standard cancer care effectively and safely

J Clin Endocrinol Metab 87(3):11291133

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Acanthosis Nigricans Symptoms One main sign of acanthosis nigricans is the thick, velvety, light-brown-to-black patch that often appears in the skin folds in the front or back of your neck, armpit, elbows, knees, belly button, or under your breast