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For instance, circ-cIARS binds to ALKBH5, an RNA-binding protein that negatively regulates ferritinophagy and ferroptosis, thereby blocking its activity (Ou et al., 2022)

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identified a specific autophagy process during H-RasV12-induced senescence, called the TOR-autophagy spatial coupling compartment (TASCC), which produced many cells that acquired the senescence-associated secretory phenotype (SASP), which promotes senescence [179]