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In this perspective, the present review combined the glutamine-dependent metabolism of NSCLC with the therapeutic strategy of targeting glutamine to provide new approaches for the treatment of NSCLC and to select those patients who may benefit the most from glutamine metabolism-targeted therapy, and ultimately to improve the overall survival rate and the long-term quality of life

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The adult human model also predicted reasonably well radioiodine in serum, thyroid, gastric contents, and urine in subjects who received an intravenous dose of radioiodine (Hays and Solomon 1965), when model parameters were calibrated to achieve good correspondence to the observations