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ATOX1 bound Cu + can also be transferred to other cytosolic enzymes requiring Cu + as well as metallothionein, a cysteine rich protein which can store to a certain extent excessive Cu + ( Figure 1 ) (24-26)

A key mechanism is the downregulation of MHC-I molecules mediated by the viral protein E5, which retains MHC-I within the Golgi and endoplasmic reticulum, reducing antigen presentation to CD8 + T cells and facilitating persistent infection (Miyauchi et al., 2023)

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Conclusion Glutathione restores the skins natural radiance and brightens skin tone

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