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In: Ballantyne CM, ed

Finally, patients were selected if their AST/ALT within 6 weeks of biopsy was greater than 2.5 times the upper limit of normal

It has a reputation for inducing increased IGF-1 (Insulin-like Growth Factor 1) secretion, a protein directly related to muscle growth and fatty acid metabolism

The most recent consensus, according to the Surviving Sepsis Campaign recommendations, are: Crystalloids are the fluid of choice for initial resuscitation and subsequent intravascular volume replacement in sepsis and septic shock (strong recommendation, moderate quality of evidence) Use albumin in addition to crystalloids when patients require substantial amounts of crystalloids (weak recommendation, low quality of evidence) I would suggest reading the following for some additional background information on the above recommendations

10.14814/phy2.70385 12 BercovichB.StancovskiI.MayerA.BlumenfeldN.LaszloA.SchwartzA.et al (1997)