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In addition, p53 can activate the expression of the iron-sulfur cluster assembly enzyme and frataxin genes, which are primarily responsible for synthesizing scaffold proteins crucial for the iron-sulfur cluster assembly process (56-58)

In contrast, we could not detect K d-la or K ce on histones by highly sensitive mass spectrometric analysis, even after enrichment

A common example is sulforaphane, found in cruciferous vegetables, which activates Nrf2, a master regulator of antioxidant pathways.74 Similarly, coenzyme Q10 supports mitochondrial health and reduces oxidative stress-related senescence.75 Key Senolytic Compounds and Their Mechanisms of Action A variety of compounds have been identified as potential senolytics, each with distinct mechanisms of action

European journal of paediatric neurology: EJPN: official journal of the European Paediatric Neurology Society2, 313-318 (1998)