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An endothelin-A and endothelin-B receptor blocker, aprocinentan, has shown promise for treating resistant hypertension by lowering blood pressure and decreasing vascular resistance

MMA is considered the most representative marker for vitamin B12 deficiency, but the low accessibility of the assay in laboratory practice reduces its clinical utility [14]

But the calculation error potential is massive

The treatment was 1,000 g/day of cyanocobalamin

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