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However, the evidence for superiority over subcutaneous administration remains unclear, and the increased complexity and discomfort of IM injection discourages its use for most individuals

Heart valve disease include aortic valve insufficiency, aortic valve stenosis, hear murmurs, aortic valve prolapse, mitral valve prolapse, tricuspid valve prolapse, mitral valve insufficiency, mitral valve stenosis, pulmonary atresia, pulmonary valve insufficiency, pulmonary valve stenosis, tricuspid atresia, tricuspid valve insufficiency, and tricuspid valve stenosis

Expert Opin Invest Drugs (2020) 29:13541

Sazanov, L

when the concentration of the polysaccharide reached 1,000 g/mL, the formation of free radicals was promoted rather than suppressed