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Acknowledgements We thank Jonathan Coloff and Samuel McBrayer for their feedback and discussions

Considering the above, it appears reasonable to include substances that would not only restore normal glycemia and tissue sensitivity to insulin but also positively affect mitochondrial functions at the stage of hyperglycemia

On the other hand, Glutathione and antioxidants enzymes have been found to protect the lung against ROS toxicity (37,38)

Variant recurrence in neurodevelopmental disorders: the use of publicly available genomic data identifies clinically relevant pathogenic missense variants

Dysken MW, Sano M, Asthana S, et al