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Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

Beside pharmacological compounds, the presence of an endogenous inhibitor of CETP in plasma has long been suspected

Considering the multifactorial nature of TMAO generation, many strategies can be pursued to reduce the level of TMA/TMAO in patients with CVDs, such as lifestyle changes, use of antibiotics and functional foods, development of related inhibitors, and improvement of gut microbiota ( Supplementary Table 4 )