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With EGFR overexpressed in TNBC, particularly basal-like subtypes, these interactions suggest that compound 2 likely impairs EGFR kinase activity by blocking ATP access, thereby inhibiting downstream signalling cascades such as PI3K/AKT and MAPK/ERK, which are central to cell proliferation, survival, and migration in TNBC

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B12 is responsible for several processes within the body, like red blood cell formation and the production of DNA

Regardless of treatment adherence, the data gathered from all participants of the study indicated a similar decrease in weight from baseline levels