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In humans, it has been observed that VIC may prevent the onset of osteoarthritis, but also vice versa, with high concentrations of VIC being associated with an increased risk of developing osteoarthritis [117] and VIC did not prevent damage to cartilage structure [117,118]

Chemical modulators of autophagy as biological probes and potential therapeutics

Journal of Controlled ReleaseBrusCSantiPColomboPKisselT2002 7

Adipose tissue serves several thermoregulatory functions: Insulation : Subcutaneous fat acts as a thermal barrier, reducing heat loss to the environment