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Met is first metabolized by methionine adenosyltransferase (MAT) to form S-adenosylmethionine (SAMe, which is also abbreviated as AdoMet) (Figure 1)

Epithelial cell and lamina propria isolation Single-cell suspensions of small intestinal epithelium and lamina propria were prepared as described previously 69,70

Ribulose-5-phosphate is a pivotal intermediate that can either be used for nucleotide biosynthesis or converted back into glycolytic intermediates, thus linking the PPP and glycolysis

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Histone methylation usually compacts the DNA, restricting the access of transcription factors necessary for gene expression