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3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects

Men over 50 may find daily activities, such as climbing stairs or walking long distances, increasingly difficult

Next-generation probiotics as novel therapeutics for improving human health: current trends and future perspectives

Animal research also supports the use of crocin in COPD: In one study that used an animal model of COPD, crocin decreased the number of immune cells and infiltration in the lungs, reduced levels of inflammatory cytokines in the lungs and brain, and decreased signs of depression, such as weight loss, appetite, and periods of immobility during physical tests (Xie 2019)

Thus for drugs known to undergo enterohepatic recirculation, the need for therapeutic drug monitoring may be necessary to ensure optimal dosing and to avoid adverse effects