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The cumulative effect of these lesions is the reduced stored cell quality and, potentially, transfusion efficacy and safety

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2020, www.sciencedirect.com/science/article/abs/pii/S0976566220304409, Wen Ting Hao, et al

Tooth Discoloration Doxycycline results in permanent staining of the deciduous teeth of the patients who are below the age of eight years, and therefore doxycycline stains the teeth