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Description

A novel anti-CD40 monoclonal antibody, iscalimab, for control of Graves hyperthyroidism-a proof-of-concept trial

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CaMKII, Ca2+/calmodulin-dependent protein kinase II

The Phase 2 Trial Data In the key Phase 2 randomized controlled trial published in the New England Journal of Medicine in 2023 (N=338), participants receiving retatrutide 12 mg weekly lost a mean of 24.2% of body weight at 48 weeks versus 2.1% on placebo [1]