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Description

The E3 Ligase MIB1 promotes proteasomal degradation of NRF2 and sensitizes lung cancer cells to ferroptosis

To consolidate our understanding of the role of SIRT7 in oncogenesis, we induced skin carcinogenesis in mice through a two-stage treatment with DMBA (7,12-dimethylbenz (alpha) anthracene) and TPA 51