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While there is a considerable body of literature describing the initial causes of copper dysregulation, there is a dearth of comprehensive exploration into the underlying pathological consequences (16)

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26 Studies have demonstrated that arginine and lysine amino acid substitution in peptides favorably facilitate insertion into bacteria membrane due to their positive charge interacting with bacterial membrane, while the presence of hydrophobic amino acids such as tryptophan and phenylalanine within peptide sequences are associated intensified antimicrobial activity against bacteria