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Description

We next performed a structural similarity search across our in-house compound collection, as well as on commercial small-molecule libraries (1,000,000 compounds) and identified 141 additional hits, which were screened in the high-throughput activity assay at a single concentration of 10 M

GSE202595 (ER + cell lines), GSE202597 (CML-exposed MDA-MB-231 cells), GSE202598 (MDA-MB-157 cell line), and GSE236420 (MDA-MB-231 and MDA-MB-468 cell lines)