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PLoS Negl Trop Dis 2(3):e194 Nair AA, Tripathy KP, Behera PK (2022) Artesunate resistance-an emerging threat

PMCID: PMC2730848.

While the rodent study was single administration, human PD studies suggest that effects dissipate fairly quickly without ongoing doses

During the stringent response, deep changes in translation, activation of transcription of amino acid synthesis genes and arrest of growth occurs, among other changes (Gallant et al