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The researchers developed indomethacin-loaded SLNs and NLCs and modified SLNs with CS chloride, a cationic water-soluble penetration enhancer

These are laboratory research observations only, are not established human or veterinary effects, and no combined effect is claimed

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USA 112 , 1128211287 (2015)

6.3 Targeting MCTs Recent study has found that inhibition of lactate influx by the monocarboxylate transporter (MCT)-1 inhibitor, AZD3965, reversed the effect of lactate on GAG accumulation and MMP3 expression and further improved NP cell degeneration in the NPD model (Wang CY