glutathione function and metabolism - an overview Glutathione Metabolism and Its Implications

discovered that dual-specificity phosphatase 16 (DUSP16) increased drug resistance by preventing the activation of the P38 MAPK pathway and the JNK pathways, which led to reduced Bax accumulation in mitochondria to reduce apoptosis (148)

488,489 Several NADs have been approved for ATTR treatment, including ASOs, such as inotersen 490,491 and eplontersen, 492 as well as siRNAs, such as patisiran 97 and vutrisiran

Zhi Z, Sun Q, Tang W

Immunogenic Nematode ES Proteins Molecules integral to the parasites growth and ability to colonize and feed on the host offer promising vaccine and anthelminthic targets

BMJ 338 , b158 (2009)