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Probiotics reduce interleukin-6 and tumor necrosis factor-alpha (TNF-) and C-reactive protein (CRP) levels to reduce peripheral and central inflammation (Leta et al., 2021)

However, limited by the objective reasons of experimental technological challenges, many critical issues still remain to be discussed and resolved

Serum FFA, glucose and lactate levels were not different between diet groups, but LCKD did lead to a 2-fold increase in -OHB (from 0.3 to 0.6 mM) and a 50% decrease in the fed-state insulin level (from 34 to 15 U/ml) compared to control