hypothesis glutathione persister cells

hypothesis glutathione persister cells Drug-tolerant in cancer: the cutting edges and future directions Frontiers | Intracellular persister: A

Name: hypothesis glutathione persister cells Drug-tolerant in cancer: the cutting edges and future directions Frontiers | Intracellular persister: A
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Frontiers Intracellular persister: A stealth agent recalcitrant to antibiotics Persister cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition PMC Mechanism of Drug Tolerant Persister Cancer Cells: The Landscape and Clinical Implication for Therapy Journal of Thoracic Oncology Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death

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doi: 10.3389/fvets.2022.854890 41 ChenYYangJHuangZYinBUmarTYangCet al

633 Chronic social defeat stress-induced depressed mice showed iron accumulation and iron homeostasis imbalance in the brain, accompanied by downregulation of GSH levels and GPX4 expression, which may be a potential mechanism of lipid peroxidation and ferroptosis in depressed mice

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Molecules 26 (22), 6994 (2021)

have revealed that ferroptosis regulates PD-L1 expression in HNSCC through a dual mechanism: on the one hand, PD-L1 is upregulated via the ROS-driven NF-B signaling pathway (a membrane damage-independent pathway), and on the other hand, immune checkpoint molecule expression is promoted through ferroptosis stress-induced calcium influx (a membrane damage-dependent pathway)