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The primers used for the construction of the above plasmids are (uppercase letters represent restriction endonuclease (RE) sequence): pJL1, Pmrp-1 SphI F 5GCATGCccagtcaacgtttcgataagttg, Pmrp-1 ApaI R 5GGGCCCttcttaattggctcggttcggt, mrp-1 CDS ApaI F 5GGGCCCatgttcccgttagttcgtgaac, mrp-1 CDS XmaI R 5CCCGGGctacacaacatttgcatcttttgc

Biochem Pharmacol 86:836843 Zhan Y, Ling Y, Deng Q, Qiu Y, Shen J, Lai H, Chen Z, Huang C, Liang L, Li X, Wu J, Huang W, Wen S (2022) HMGB1-mediated neutrophil extracellular trap formation exacerbates intestinal ischemia/reperfusion-induced acute lung injury

Antioxidants can be incorporated into magnetic nanoparticles and then guided to a tumour site through exposure to an external magnetic field

Their design must strike a balance between ultra-high potency, sufficient chemical stability, and favorable physicochemical properties [91, 92]

Glutathione-S-transferase catalyzes the conjugation of NAPQI with GSH, forming APAP-GSH adducts, 9,10 which are further metabolized into nontoxic thiolate and cysteine molecules, including adducts of cysteamide, glycine/cysteine, and N-acetyl-L-cysteine