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A common DIO2 haplotype composed of the minor C-allele of SNP rs225014 and the common C-allele of SNP rs12885300 was significantly associated with advanced hip OA, as indicated by a higher odds ratio 101,102,103

The same vector was used to create the recombinant strains

Especially in the past half century, global warming has driven drier environment and higher water evaporation, as a result, leading to mucus thinning, epithelial compression and subsequent inflammation 289

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