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Compared with current therapies for RA, which show success in targeting various aspects of inflammatory pathways, the SP-based therapy in this work targeting both the synovial inflammation and RANKL-induced osteoclast differentiation is more promising as an off-the-shelf therapeutic for the alleviation of RA

Assiri MA, Al Jumayi SR, Alsuhaymi S, Emwas AH, Jaremko M, Alsaleh NB, Al Mutairi MM, Alshamrani AA, As Sobeai H, Alghibiwi H (2024) Electronic cigarette vapor disrupts key metabolic pathways in human lung epithelial cells

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GSH prevents LOsG-induced pancreatic fibrosis via the TGF/SMAD pathway in vivo Considering the crucial role of TGF-1 in organ fibrosis, we examined whether LOsG contributed to TGF-1 expression by detecting TGF-1 protein levels in pancreatic tissues using western blotting