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Similarly, Degner et al

IL-7/IL-7R signaling IL-7/IL-7R signaling is essential for peripheral homeostasis and the survival, differentiation, and maintenance of T cells including CD4 + T, CD8 + T, naive T, and memory T cells

One representative agent is curcumin, a plant-based NF-B inhibitor, which has been confirmed in various tumor-bearing mouse models to exert antitumor effects with elevated tumor-suppressing effector immune cells, including CD8 + T cells, NK cells and M1 macrophages, and constrained immunosuppressive cells, including Tregs and MDSCs