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controls (Unnithan et al., 2015

2014, (Handout)

Nature 460 , 11361139 (2009)

It is also why rushing to a higher dose in the first week or two before steady state is reached often leads to unnecessary side effects

Authors concluded that combining NRT with behaviour change counselling resulted in a significantly higher quit rates and lower cotinine levels, but significant impact on patient-related or microbiological outcomes were not detected (Sharma et al., 2018)